Male-to-female (MTF) transition medication typically involves hormone replacement therapy (HRT) to induce feminizing changes in the body.
The two main types of medications used in MTF HRT are anti-androgens and estrogen.
⦁ Anti-androgens: These medications are used to suppress the effects of testosterone, which is the primary male sex hormone. By reducing testosterone levels, anti-androgens help feminize the body and promote the development of feminine characteristics.
Some commonly used anti-androgens include:
⦁ Spironolactone: It is a medication that blocks the effects of androgens and is commonly used in MTF HRT.
⦁ Cyproterone acetate: This medication has anti-androgenic properties and is used in some countries for MTF HRT.
⦁ GnRH agonists: Medications like leuprorelin and goserelin can be used to suppress the production of testosterone by the testes.
⦁ Estrogen: Estrogen is the primary female sex hormone, and adding it to the body helps promote feminization. Estrogen can be administered through various methods, including oral pills, transdermal patches, or injections. Commonly prescribed forms of estrogen for MTF HRT include:
⦁ Estradiol: This is the most commonly used form of estrogen and is available in various formulations.
⦁ Estrogen esters: Medications like estradiol valerate or estradiol cypionate are longer-acting forms of estrogen that can be administered via injection.
The specific medications, dosages, and administration methods can vary based on individual needs, health factors, and preferences. It’s crucial to consult with a healthcare professional experienced in transgender healthcare, such as an endocrinologist or a gender specialist, who can provide personalized guidance and monitor your hormone levels throughout the transition process. Regular check-ups and blood tests are typically necessary to ensure appropriate hormone levels and overall health.