Hormone replacement therapy (HRT) for transgender individuals, also known as transgender hormone therapy or hormone replacement therapy for transgender people, is a medical intervention that involves the administration of hormones to bring about physical changes consistent with a person’s gender identity.

For transgender individuals seeking masculinization (transmasculine individuals, assigned female at birth), testosterone is typically prescribed as the primary hormone. Testosterone is administered through intramuscular injections, transdermal patches, or topical gels/creams. The therapy aims to induce the development of secondary male sexual characteristics, such as facial and body hair growth, voice deepening, and increased muscle mass.

For individuals seeking feminization (transfeminine individuals, assigned male at birth), estrogen and anti-androgens are usually prescribed. Estrogen can be administered orally, through skin patches, or by injection. Anti-androgens, such as spironolactone or cyproterone acetate, are used to block or reduce the effects of testosterone, allowing estrogen to have a feminizing impact. These medications can promote breast development, redistribution of body fat, decreased body hair, and other feminizing changes.

The specific dosage and treatment plan for hormone replacement therapy will depend on various factors, including an individual’s overall health, age, and personal goals. It is essential to undergo HRT under the supervision of a qualified healthcare professional experienced in transgender care. They can monitor hormone levels, manage potential side effects, and provide necessary support throughout the process.

It’s important to note that hormone replacement therapy is just one aspect of the overall transition process for transgender individuals. Mental health support, social transition, and, in some cases, surgical interventions may also be components of a person’s transition journey.